Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary
نویسندگان
چکیده
منابع مشابه
Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary
MOTIVATION High-throughput technologies such as DNA sequencing and microarrays have created the need for automated annotation of large sets of genes, including whole genomes, and automated identification of pathways. Ontologies, such as the popular Gene Ontology (GO), provide a common controlled vocabulary for these types of automated analysis. Yet, while GO offers tremendous value, it also has...
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The KEGG Orthology (KO) database was tested as a source for automated annotation of expressed sequence tags (ESTs). We used a control experiment where every EST was assigned to its cognate protein, and an annotation experiment where the ESTs were annotated by proteins from other organisms. Analyzing the results, we could assign classes to the annotation: correct, changed and speculated. The cor...
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MOTIVATION Regulation of gene expression in space and time directs its localization to a specific subset of cells during development. Systematic determination of the spatiotemporal dynamics of gene expression plays an important role in understanding the regulatory networks driving development. An atlas for the gene expression patterns of fruit fly Drosophila melanogaster has been created by who...
متن کاملKEGG as a reference resource for gene and protein annotation
KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an integrated database resource for biological interpretation of genome sequences and other high-throughput data. Molecular functions of genes and proteins are associated with ortholog groups and stored in the KEGG Orthology (KO) database. The KEGG pathway maps, BRITE hierarchies and KEGG modules are developed as networks of KO nodes, ...
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از آنجا که یادگیری لغت یکی از پایه های اساسی فراگیری زبان خارجی است و در سیستم آموزش و پرورش وقت بسیار کمی به آموزش زبان انگلیسی اختصاص داده شده است محقق برآنست به بررسی سه فعالیت که گمان می رود به بسط دانش واژگانی فراگیران کمک می کنند بپردازد.
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2005
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bti430